NBC19 |CAS:2068818-75-5 Probechem Biochemicals

Chemical Structure : NBC19

NBC19 (NBC 19)

Catalog No.: PC-63450Not For Human Use, Lab Use Only.

NBC19 is a potent inhibitor of NLRP3 inflammasome, inhibits nigericin-induced ASC speck formation in post-differentiated THP1 cells with IC50 of 60 nM..

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Biological Activity

NBC19 is a potent inhibitor of NLRP3 inflammasome, inhibits nigericin-induced ASC speck formation in post-differentiated THP1 cells with IC50 of 60 nM.

Physicochemical Properties

M.Wt	491.644
Formula	C24H26BCl3N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(6-(cyclohexylamino)-2,2-diphenyl-4-(trichloromethyl)-2,3-dihydro-1l3,3,2l4-oxazaborinin-5-yl)ethan-1-one

References

1. Redondo-Castro E, et al. Sci Rep. 2018 Apr 4;8(1):5667.

2. Baldwin AG, et al. Cell Chem Biol. 2017 Nov 16;24(11):1321-1335.e5.

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NBC19 (NBC 19)

Biological Activity

Physicochemical Properties

References

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