Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : NC-005
Catalog No.: PC-60970Not For Human Use, Lab Use Only.
NC-005 is a potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 44 nM, 105 and 225-fold selectivity over β2i and β1i subunit, respecitvely.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
NC-005 is a potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 44 nM, 105 and 225-fold selectivity over β2i and β1i subunit, respecitvely.
NC-005 shows cytotoxicity against multiple myeloma cells with IC50 of 30 nM-1.5 uM.
| M.Wt | 663.815 | |
| Formula | C40H45N3O6 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Britton M, et al. Chem Biol. 2009 Dec 24;16(12):1278-89.
2. de Bruin G, et al. J Med Chem. 2014 Jul 24;57(14):6197-209.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
