NCD-25 |CAS:1456972-46-5 Probechem Biochemicals

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Chemical Structure : NCD-25

NCD-25 (NCD25;NCD 25)

Catalog No.: PC-61956Not For Human Use, Lab Use Only.

NCD-25 is a novel potent, selective LSD1 inhibitor with IC50 of 0.48 uM, exerts highly selective inhibitory activity on LSD1 but no other enzymes, such as MAO..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

NCD-25 is a novel potent, selective LSD1 inhibitor with IC50 of 0.48 uM, exerts highly selective inhibitory activity on LSD1 but no other enzymes, such as MAO.

Physicochemical Properties

M.Wt	531.7
Formula	C35H37N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((2S)-1-(benzylamino)-1-oxo-6-((2-phenylcyclopropyl)amino)hexan-2-yl)-[1,1'-biphenyl]-4-carboxamide

References

1. Miyamura S, et al. Org Biomol Chem. 2016 Sep 28;14(36):8576-85.

2. Sugino N, et al. Leukemia. 2017 Nov;31(11):2303-2314.

3. Ogasawara D, et al. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8620-4.

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NCD-25 (NCD25;NCD 25)

Biological Activity

Physicochemical Properties

References

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