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NCD-25

Chemical Structure : NCD-25

CAS No.: 1456972-46-5

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NCD-25 (NCD25;NCD 25)

Catalog No.: PC-61956Not For Human Use, Lab Use Only.

NCD-25 is a novel potent, selective LSD1 inhibitor with IC50 of 0.48 uM, exerts highly selective inhibitory activity on LSD1 but no other enzymes, such as MAO..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    NCD-25 is a novel potent, selective LSD1 inhibitor with IC50 of 0.48 uM, exerts highly selective inhibitory activity on LSD1 but no other enzymes, such as MAO.

    Physicochemical Properties

    M.Wt 531.7
    Formula C35H37N3O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-((2S)-1-(benzylamino)-1-oxo-6-((2-phenylcyclopropyl)amino)hexan-2-yl)-[1,1'-biphenyl]-4-carboxamide

    References

    1. Miyamura S, et al. Org Biomol Chem. 2016 Sep 28;14(36):8576-85.

    2. Sugino N, et al. Leukemia. 2017 Nov;31(11):2303-2314.

    3. Ogasawara D, et al. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8620-4.

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