Catalog No.: PC-26938Not For Human Use, Lab Use Only.
NCGC00188636 (DBS) is a covalent inhibitor of pyruvate kinase (PYK) with IC50 of Leishmania mexicana PYK (LmPYK), inhibits both HsRPYK (the human PYK isoenzyme present in erythrocytes) and HsM2PYK (the human PYK isoenzyme present in embryonic and tumour cells) with IC50 values of 8 uM and 16.3 uM, respectively.
NCGC00188636 (DBS) is a covalent inhibitor of pyruvate kinase (PYK) with IC50 of Leishmania mexicana PYK (LmPYK), inhibits both HsRPYK (the human PYK isoenzyme present in erythrocytes) and HsM2PYK (the human PYK isoenzyme present in embryonic and tumour cells) with IC50 values of 8 uM and 16.3 uM, respectively. NCGC00188636 (DBS) blocks nucleotide binding to the active site of pyruvate kinase, reacts with Lys335 at the active site of LmPYK.
