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NCT-504

Chemical Structure : NCT-504

CAS No.: 1222765-97-0

NCT-504 (NCT504)

Catalog No.: PC-38272Not For Human Use, Lab Use Only.

NCT-504 (NCT504) is a selective inhibitor of PI5P4Kγ with IC50 of 16 uM in 32P-ATP/PI5P incorporation assay, high selectivity against a panel of 442 kinases.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

NCT-504 (NCT504) is a selective inhibitor of PI5P4Kγ with IC50 of 16 uM in 32P-ATP/PI5P incorporation assay, high selectivity against a panel of 442 kinases.

Physicochemical Properties

M.Wt 404.481
Formula C15H12N6O2S3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO (4.0 mg/mL)

Chemical Name/SMILES

4-((1-methyl-1H-tetrazol-5-yl)thio)-5-(3-(methylsulfonyl)phenyl)thieno[2,3-d]pyrimidine

References

1. Helen K Boffey, et al. J Med Chem. 2022 Feb 11. doi: 10.1021/acs.jmedchem.1c01819.

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