NEK2 inhibitor INH6 |CAS 1001753-24-7 Probechem Biochemicals

Chemical Structure : NEK2 inhibitor INH6

CAS No.: 1001753-24-7

NEK2 inhibitor INH6 (INH6)

Catalog No.: PC-42194Not For Human Use, Lab Use Only.

NEK2 inhibitor INH6 is a small molecule inhibitor of Nek2/Hec1 that inhibits cell growth of MB231, MB468, HeLa and K562 cells with IC50 of 1.7, 2.1, 2.4 and 2.5 uM, respectively.

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Biological Activity

INH6 is a small molecule inhibitor of Nek2/Hec1 that inhibits cell growth of MB231, MB468, HeLa and K562 cells with IC50 of 1.7, 2.1, 2.4 and 2.5 uM, respectively.
INH6 triggers mitotic abnormalities and induces apoptosis.

Physicochemical Properties

M.Wt	322.424
Formula	C19H18N2OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzamide, N-[4-(2,4,6-trimethylphenyl)-2-thiazolyl]-

References

1. Qiu XL, et al. J Med Chem. 2009 Mar 26;52(6):1757-67.

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NEK2 inhibitor INH6 (INH6)

Biological Activity

Physicochemical Properties

References

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