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Chemical Structure : NEK6 inibitor 8
CAS No.: 591239-68-8
Catalog No.: PC-35735Not For Human Use, Lab Use Only.
NEK6 inibitor 8 (ZINC05007751) is a novel inhibitor of the NIMA-related kinase NEK6 with IC50 of 3.4 uM, compound 8 is very selective against NEK1 and NEK6, while no signifcant activity was observed against NEK2, NEK7, and NEK9.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $288 | In stock | |
| 25 mg | $458 | In stock | |
| 100 mg | Get quote |
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NEK6 inibitor 8 (ZINC05007751) is a novel inhibitor of the NIMA-related kinase NEK6 with IC50 of 3.4 uM, compound 8 is very selective against NEK1 and NEK6, while no signifcant activity was observed against NEK2, NEK7, and NEK9.
NEK6 inibitor 8 dispalys antiproliferative activity against a panel of human cancer cell lines (IC50 <100 uM).
| M.Wt | 304.305 | |
| Formula | C18H12N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(5Z)-2-hydroxy-4-methyl-6-oxo-5-[(5-phenylfuran-2-yl)methylidene]-5,6-dihydropyridine-3-carbonitrile |
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1. De Donato M, et al. Sci Rep. 2018 Oct 30;8(1):16047.
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