NEU-1953 |CAS:2218480-85-2 Probechem Biochemicals

Chemical Structure : NEU-1953

Catalog No.: PC-35984Not For Human Use, Lab Use Only.

NEU-1953 (NEU1953) is a potent inhibitor of P. falciparum with EC50 of 0.43 uM (T. brucei), demonstrates improved ADME profile over the NEU-961..

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Biological Activity

NEU-1953 (NEU1953) is a potent inhibitor of P. falciparum with EC50 of 0.43 uM (T. brucei), demonstrates improved ADME profile over the NEU-961.

M.Wt	398.474
Formula	C22H22N8
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	7-(2-(4-methylpiperazin-1-yl)pyrimidin-5-yl)-N-(pyrazin-2-yl)quinolin-4-amine

1. Mehta N, et al. ACS Infect Dis. 2018 Apr 13;4(4):577-591.

2. Bachovchin KA, et al. J Med Chem. 2018 Dec 19. doi: 10.1021/acs.jmedchem.8b01365.