NF2839 | SmHDAC8 inhibitor | Probechem Biochemicals

Chemical Structure : NF2839

NF2839 (NF 2839, NF-2839)

Catalog No.: PC-21960Not For Human Use, Lab Use Only.

NF2839 is a quinolone-based HDAC inhibitor with IC50 of 0.1 uM for S. mansoni HDAC8 (SmHDAC8), inhibits S. mansoni larval stage with LD50 of 10.6 uM.

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Biological Activity

NF2839 is a quinolone-based HDAC inhibitor with IC50 of 0.1 uM for S. mansoni HDAC8 (SmHDAC8), inhibits S. mansoni larval stage with LD50 of 10.6 uM.

Physicochemical Properties

M.Wt	561.68
Formula	C35H35N3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(((1-(4-((diethylamino)methyl)benzyl)-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)oxy)methyl)-N-hydroxybenzamide

References

1. Roberto Gimmelli, et al. PLoS Negl Trop Dis. 2024 Feb 28;18(2):e0011992.

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NF2839 (NF 2839, NF-2839)

Biological Activity

Physicochemical Properties

References

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