NGD61181 | SHIP2 inhibitor | Probechem Biochemicals

Chemical Structure : NGD61181

NGD61181 (NGD 61181)

Catalog No.: PC-21456Not For Human Use, Lab Use Only.

NGD61181 is a pyrazole-based SHIP2 inhibitor, has micromolar binding affinity and inhibitory activity, does not contain a phosphatase “warhead,” binds the active site of SHIP2.

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Biological Activity

NGD61181 is a pyrazole-based SHIP2 inhibitor, has micromolar binding affinity and inhibitory activity, does not contain a phosphatase “warhead,” binds the active site of SHIP2.

Physicochemical Properties

M.Wt	518.60
Formula	C31H32F2N2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-2-((3-(azepane-1-carbonyl)-2',4'-difluoro-[1,1'-biphenyl]-4-yl)oxy)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide

References

1. Annis DA, et al. Comb Chem High Throughput Screen. 2009; 12(8): 760-771.

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NGD61181 (NGD 61181)

Biological Activity

Physicochemical Properties

References

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