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NGD61181

Chemical Structure : NGD61181

CAS No.: 1266401-14-2

NGD61181 (NGD 61181)

Catalog No.: PC-21456Not For Human Use, Lab Use Only.

NGD61181 is a pyrazole-based SHIP2 inhibitor, has micromolar binding affinity and inhibitory activity, does not contain a phosphatase “warhead,” binds the active site of SHIP2.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NGD61181 is a pyrazole-based SHIP2 inhibitor, has micromolar binding affinity and inhibitory activity, does not contain a phosphatase “warhead,” binds the active site of SHIP2.

Physicochemical Properties

M.Wt 518.60
Formula C31H32F2N2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-2-((3-(azepane-1-carbonyl)-2',4'-difluoro-[1,1'-biphenyl]-4-yl)oxy)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide

References

1. Annis DA, et al. Comb Chem High Throughput Screen. 2009; 12(8): 760-771.

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