NJH-2-030 | FEM1B E3 ligand | Probechem Biochemicals

Chemical Structure : NJH-2-030

CAS No.: 2709040-02-6

NJH-2-030 (EN106 derivative 3)

Catalog No.: PC-38766Not For Human Use, Lab Use Only.

EN106 derivative 3 is a EN106 derivative used for PROTAC design, EN106 is a covalent ligand and recruiter for FEM1B E3 ligase for targeted protein degradation.

Packing	Price	Stock
5 mg	$258	In stock
10 mg	$398	In stock
25 mg	$598	In stock
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Biological Activity

EN106 derivative 3 is a EN106 derivative used for PROTAC design, EN106 is a covalent ligand and recruiter for FEM1B E3 ligase for targeted protein degradation.

Physicochemical Properties

M.Wt	373.83
Formula	C19H20ClN3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Chloro-N-(2-cyanoethyl)-N-(4-(hex-5-ynoyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl)acetamide

References

1. Nathaniel J. Henning, et al. J. Am. Chem. Soc. 2022, 144, 2, 701–708.

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NJH-2-030 (EN106 derivative 3)

Biological Activity

Physicochemical Properties

References

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