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NK-189

Chemical Structure : NK-189

CAS No.: 2493976-08-0

NK-189 (NK189)

Catalog No.: PC-23173Not For Human Use, Lab Use Only.

NK-189 is a potent, specific flaviviral serine protease NS2B-NS3 inhibitor with submicromolar activities in viral replication assays (EC50=0.89 μM, DENV-2).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NK-189 is a potent, specific flaviviral serine protease NS2B-NS3 inhibitor with submicromolar activities in viral replication assays (EC50=0.89 μM, DENV-2).

Physicochemical Properties

M.Wt 501.63
Formula C29H35N5O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-N-(1-(4-(benzyloxy)phenyl)-2-((4-guanidinobenzyl)amino)-2-oxoethyl)hexanamide

References

1. Nikos Kühl, et al. J Med Chem. 2020 Aug 13;63(15):8179-8197.

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