NK-189 | NS2B-NS3 inhibitor | Probechem Biochemicals

Chemical Structure : NK-189

NK-189 (NK189)

Catalog No.: PC-23173Not For Human Use, Lab Use Only.

NK-189 is a potent, specific flaviviral serine protease NS2B-NS3 inhibitor with submicromolar activities in viral replication assays (EC50=0.89 μM, DENV-2).

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Biological Activity

NK-189 is a potent, specific flaviviral serine protease NS2B-NS3 inhibitor with submicromolar activities in viral replication assays (EC50=0.89 μM, DENV-2).

Physicochemical Properties

M.Wt	501.63
Formula	C29H35N5O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-(1-(4-(benzyloxy)phenyl)-2-((4-guanidinobenzyl)amino)-2-oxoethyl)hexanamide

References

1. Nikos Kühl, et al. J Med Chem. 2020 Aug 13;63(15):8179-8197.

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NK-189 (NK189)

Biological Activity

Physicochemical Properties

References

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