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NK192

Chemical Structure : NK192

CAS No.: 1959552-23-8

NK192 (NK-192)

Catalog No.: PC-26806Not For Human Use, Lab Use Only.

NK192 is a potent, selective USP7 inhibitor with IC50 of 20 nM, shows proteome-wide specificity.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NK192 is a potent, selective USP7 inhibitor with IC50 of 20 nM, shows proteome-wide specificity.

Physicochemical Properties

M.Wt 489.55
Formula C27H28FN5O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-1-(4-fluorophenyl)-5-((4-hydroxy-1-(3-phenylbutanoyl)piperidin-4-yl)methyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

References

1. Klink N, et al. Nat Commun. 2026 May 13;17(1):4331.

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