NOD-IN-1 | NOD1/NOD2 inhibitor | Probechem Biochemicals

Chemical Structure : NOD-IN-1

CAS No.: 132819-92-2

NOD-IN-1 (NOD1/NOD2 inhibitor)

Catalog No.: PC-42228Not For Human Use, Lab Use Only.

NOD-IN-1 is a potent, dual inhibitor of NOD1 and NOD2 with IC50 of 5.74 uM and 6.45 uM, respectively.

Packing	Price	Stock
5 mg	$128	In stock
10 mg	$198	In stock
25 mg	$358	In stock
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Biological Activity

NOD-IN-1 is a potent, dual inhibitor of NOD1 and NOD2 with IC50 of 5.74 uM and 6.45 uM, respectively.
NOD-IN-1 is 7-fold less potent than Noditinib-1 in terms of NOD1 inhibition and completely devoid of selective activity for NOD1 or NOD2 as opposed to Noditinib-1.

Physicochemical Properties

M.Wt	343.3969
Formula	C18H17NO4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl ester

References

1. Keček Plešec K, et al. Bioorg Med Chem. 2016 Nov 1;24(21):5221-5234.

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