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Chemical Structure : NOFD
Catalog No.: PC-60851Not For Human Use, Lab Use Only.
NOFD (N-oxalyl-d-phenylalanine) is a specific HIF asparaginyl hydroxylase (FIH) inhibitor with Ki of 83 uM, but not HIF prolyl hydroxylase (>1 mM).
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NOFD (N-oxalyl-d-phenylalanine) is a specific HIF asparaginyl hydroxylase (FIH) inhibitor with Ki of 83 uM, but not HIF prolyl hydroxylase (>1 mM).
NOFD also shows lack of in vitro inhibitory activities against a panel of Jumonji-C containing proteins KDM3A, KDM4E, and KDM6B (IC50>20 uM).
| M.Wt | 237.211 | |
| Formula | C11H11NO5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. McDonough MA, et al. J Am Chem Soc. 2005 Jun 1;127(21):7680-1.
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