Chemical Structure : NOXA1ds
CAS No.: 1435893-78-9
Catalog No.: PC-24326Not For Human Use, Lab Use Only.
NoxA1ds is a potent and highly selective NADPH oxidase 1 (NOX1) inhibitor with IC50 of 20 nM, potently inhibits Nox1-derived superoxide anion (O2·-) production with no effect on Nox2-, Nox4-, Nox5-, or xanthine oxidase-derived reactive oxygen species production.
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NoxA1ds is a potent and highly selective NADPH oxidase 1 (NOX1) inhibitor with IC50 of 20 nM, potently inhibits Nox1-derived superoxide anion (O2·-) production with no effect on Nox2-, Nox4-, Nox5-, or xanthine oxidase-derived reactive oxygen species production.
M.Wt | 1125.32 | |
Formula | C50H88N14O15 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(3S,6S,9S,12S,18S,21S,24S)-24-((S)-2-((S)-1-(L-glutamyl)pyrrolidine-2-carboxamido)-3-methylbutanamido)-6,12-bis(4-aminobutyl)-3-carbamoyl-18-isobutyl-2,9,21-trimethyl-5,8,11,14,17,20,23-heptaoxo-4,7,10,13,16,19,22-heptaazahexacosan-26-oic acid |
1. Ranayhossaini DJ, et al. J Biol Chem. 2013 Dec 20;288(51):36437-50.
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