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NRP2945

Chemical Structure : NRP2945

CAS No.: 1145786-97-5

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NRP2945 (NRP-2945)

Catalog No.: PC-28238Not For Human Use, Lab Use Only.

NRP2945 (NRP-2945) is a neuroactive peptidomimetic analogue of the human CAPS-2 protein (calcium- dependent activator of protein secretion 2), upregulates the expression of GABAA receptor α and β subunits, increases neuronal survival and differentiation, exerts many potentially anti-epileptic effects.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    NRP2945 (NRP-2945) is a neuroactive peptidomimetic analogue of the human CAPS-2 protein (calcium- dependent activator of protein secretion 2), upregulates the expression of GABAA receptor α and β subunits, increases neuronal survival and differentiation, exerts many potentially anti-epileptic effects.

    Physicochemical Properties

    M.Wt 1038.19
    Formula C41H75N21O11
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    Glycinamide, glycyl-L-arginyl-L-arginyl-L-alanyl-L-alanyl-L-prolylglycyl-L-arginyl-2-methylalanylglycyl-

    References

    1. Sajadian A, et al. Neuropeptides. 2015 Feb;49:15-23.

    2. Lovisari F, et al. Eur J Pharmacol. 2021 Jun 15;901:174068.

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