Chemical Structure : NS-018 maleate
CAS No.:
1354799-87-3
NS-018 maleate
(NS018 maleate, Ilginatinib maleate)
Catalog No. : PC-45662Not For Human Use, Lab Use Only.
NS-018 maleate (NS018, Ilginatinib) is a potent and highly selective JAK2 inhibitor (IC50=0.72 nM).
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4566201
Biological Activity
NS-018 maleate (NS018, Ilginatinib) is a potent and highly selective JAK2 inhibitor (IC50=0.72 nM).
Physicochemical Properties
M.Wt
505.501
Formula
C25H24FN7O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 30 mg/mL
Chemical Name/SMILES
2,6-Pyridinediamine, N2-[(1S)-1-(4-fluorophenyl)ethyl]-4-(1-methyl-1H-pyrazol-4-yl)-N6-2-pyrazinyl-, (2Z)-2-butenedioate (1:1)
References
1. Nakaya Y, et al. Blood Cancer J.
2. Nakaya Y, et al. Blood Cancer J.
3. Kuroda J, et al. Leuk Res.
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