Catalog No.: PC-42797Not For Human Use, Lab Use Only.
NS11394 is a potent, subtype-selective, orally available GABAA receptor positive modulator with Ki of 0.4, 0.8, 0.5 and 0.1 nM for α1, α2, α3 and α5 subunits together with β3γ2.
NS11394 is a potent, subtype-selective, orally available GABAA receptor positive modulator with Ki of 0.4, 0.8, 0.5 and 0.1 nM for α1, α2, α3 and α5 subunits together with β3γ2.
NS11394 displays 600 to 2000-fold over GABAA-α4 or GABAA-α6 containing receptors.
NS11394 exhibits in vivo anxiolytic efficacy, attenuates spontaneous nociceptive behaviors in response to hindpaw injection of formalin and capsaicin in rats.
