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NS16085

Chemical Structure : NS16085

CAS No.: 1227253-85-1

NS16085 (NS 16085, NS-16085)

Catalog No.: PC-22281Not For Human Use, Lab Use Only.

NS16085 is a potent, selective alpha2/alpha3 subtype-selective GABA(A) receptor positive allosteric modulator, dsplays negligible efficacy at GABAA-α5 receptors.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NS16085 is a potent, selective alpha2/alpha3 subtype-selective GABA(A) receptor positive allosteric modulator, dsplays negligible efficacy at GABAA-α5 receptors.

Physicochemical Properties

M.Wt 388.86
Formula C22H17ClN4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-chloro-3-{6-[5-(2-hydroxypropan-2-yl)-1H-1,3-benzodiazol-1-yl]pyridin-2-yl}benzonitrile

References

1. de Lucas AG, et al. Biochem Pharmacol. 2015 Feb 1;93(3):370-9.

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