NSC157058 | NS2B-NS3 inhibitor | Probechem Biochemicals

Chemical Structure : NSC157058

Catalog No.: PC-23171Not For Human Use, Lab Use Only.

NSC157058 is a potent, allosteric inhibitor of ZIKV NS2B-NS3 protease with IC50 of 0.82 uM.

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Biological Activity

NSC157058 is a potent, allosteric inhibitor of ZIKV NS2B-NS3 protease with IC50 of 0.82 uM.

M.Wt	189.99
Formula	C4HCl2N5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5,6-dichloro-2H-[1,2,3]triazolo[4,5-b]pyrazine

1. Shiryaev S.A., et al. Antivir. Res. 2017;143:218–229.

2. Lorenzo Cavina, et al. Molecules. 2024 Aug 27;29(17):4047.