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NSC157058

Chemical Structure : NSC157058

CAS No.: 1135191-02-4

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NSC157058 (NSC 157058)

Catalog No.: PC-23171Not For Human Use, Lab Use Only.

NSC157058 is a potent, allosteric inhibitor of ZIKV NS2B-NS3 protease with IC50 of 0.82 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NSC157058 is a potent, allosteric inhibitor of ZIKV NS2B-NS3 protease with IC50 of 0.82 uM.

Physicochemical Properties

M.Wt 189.99
Formula C4HCl2N5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5,6-dichloro-2H-[1,2,3]triazolo[4,5-b]pyrazine

References

1. Shiryaev S.A., et al. Antivir. Res. 2017;143:218–229.

2. Lorenzo Cavina, et al. Molecules. 2024 Aug 27;29(17):4047.

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