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NSC158011

Chemical Structure : NSC158011

CAS No.: 201015-15-8

NSC158011 (NSC-158011)

Catalog No.: PC-28469Not For Human Use, Lab Use Only.

NSC158011 (NSC-158011) is a small molecule inhibitor of P. falciparum phosphoethanolamine N-methyltransferase (PfPMT), inhibits phosphatidylcholine (PC) biosynthesis, shows strong gametocytocidal activity.

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Biological Activity

NSC158011 (NSC-158011) is a small molecule inhibitor of P. falciparum phosphoethanolamine N-methyltransferase (PfPMT), inhibits phosphatidylcholine (PC) biosynthesis, shows strong gametocytocidal activity.

Physicochemical Properties

M.Wt 309.45
Formula C18H15NS2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(Naphthalen-1-yl)-2-(phenylthio)ethanethioamide

References

1. Frieman M, et al. PLoS One. 2011;6(12):e28479.

2. Bobenchik AM, et al. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18262-7.

3. Garg A, et al. Sci Rep. 2015 Mar 12;5:9064.

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