Chemical Structure : NSC319726
CAS No.:
71555-25-4
NSC319726
(NSC 319726, ZMC1)
Catalog No. : PC-45497Not For Human Use, Lab Use Only.
NSC319726 (NSC 319726, ZMC1) is an allele-specific mutant p53 R175 reactivator, restores WT structure and function to the p53(R175) mutant.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4549701
Biological Activity
NSC319726 (NSC 319726, ZMC1) is an allele-specific mutant p53 R175 reactivator, restores WT structure and function to the p53(R175) mutant.
Physicochemical Properties
M.Wt
234.3207
Formula
C11H14N4S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: 27.5 mg/mL
Chemical Name/SMILES
1-Azetidinecarbothioic acid, 2-[1-(2-pyridinyl)ethylidene]hydrazide
References
1. Yu X, et al. Cancer Cell.
2. Yu X, et al. Oncotarget.
3. Yu X, et al. Mol Pharmacol.
4. Shimada K, et al. Cell Chem Biol.
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