NSC405020 (NSC 405020)

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Chemical Structure : NSC405020

CAS No.: 7497-07-6

Catalog No.: PC-28744Not For Human Use, Lab Use Only.

NSC405020 (NSC 405020) is a selective matrix metalloproteinase-14 (MMP14, MT1-MMP) inhibitor, interacts with the hemopexin (PEX) domain of MMP14, represses tumor growth and causes a fibrotic, ΔPEX-like tumor phenotype in vivo.

Packing	Price	Stock
25 mg	$78	In stock
50 mg	$118	In stock
100 mg	$188	In stock
250 mg		Get quote

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

NSC405020 (NSC 405020) is a selective matrix metalloproteinase-14 (MMP14, MT1-MMP) inhibitor, interacts with the hemopexin (PEX) domain of MMP14, represses tumor growth and causes a fibrotic, ΔPEX-like tumor phenotype in vivo.

Physicochemical Properties

M.Wt	260.16
Formula	C12H15Cl2NO
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3,4-Dichloro-N-(pentan-2-yl)benzamide

References

1. Thang ND, et al. PLoS One. 2014 May 9;9(5):e96945.

2. Kittaka M, et al. J Bone Miner Res. 2018 Jan;33(1):167-181.

3. Albert G Remacle, et al. Cancer Res. 2012 May 1;72(9):2339-49.

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