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NSC 630668

Chemical Structure : NSC 630668

CAS No.: 330846-35-0

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NSC 630668 (NSC630668)

Catalog No.: PC-62569Not For Human Use, Lab Use Only.

NSC 630668 is a Hsc70 inhibitor that inhibits the endogenous and DnaJ-stimulated ATPase activity of hsc70.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    NSC 630668 is a Hsc70 inhibitor that inhibits the endogenous and DnaJ-stimulated ATPase activity of Hsc70.
    NSC 630668 blocks the hsc70-mediated translocation of a preprotein into yeast endoplasmic reticulum-derived microsomal vesicles.

    Physicochemical Properties

    M.Wt 822.8591
    Formula C36H54N8O14
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    bis(6-(5-((ethoxycarbonyl)carbamoyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)hexyl) hexane-1,6-diyldicarbamate

    References

    1. Fewell SW, et al. J Biol Chem. 2001 Jan 12;276(2):910-4.

    2. Fewell SW, et al. J Biol Chem. 2004 Dec 3;279(49):51131-40.

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