NSC 65828 | Angiogenin inhibitor | Probechem Biochemicals

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Chemical Structure : NSC 65828

NSC 65828 (NCI 65828)

Catalog No.: PC-70238Not For Human Use, Lab Use Only.

NSC 65828 (NCI65828) is a small-molecule inhibitor of the ribonucleolytic activity of human angiogenin with Ki of 81 uM.

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Biological Activity

NSC 65828 (NCI65828) is a small-molecule inhibitor of the ribonucleolytic activity of human angiogenin with Ki of 81 uM; possess antitumor activity in mice.

Physicochemical Properties

M.Wt	419.455
Formula	C22H17N3O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	8-amino-5-((4'-hydroxy-[1,1'-biphenyl]-4-yl)diazenyl)naphthalene-2-sulfonic acid

References

1. Kao RY, et al. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):10066-71.

2. Jenkins JL, et al. Biochemistry. 2003 Jun 10;42(22):6674-87.

3. Seibert C, et al. Virology. 2006 May 25;349(1):41-54.

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NSC 65828 (NCI 65828)

Biological Activity

Physicochemical Properties

References

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