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NSI-189

Chemical Structure : NSI-189

CAS No.: 1270138-40-3

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NSI-189 (NSI 189)

Catalog No.: PC-22685Not For Human Use, Lab Use Only.

NSI-189 is an orally active benzylpiperizine-aminiopyridine compound with neurogenic activity, stimulates neurogenesis of human hippocampus-derived neural stem cells in vitro and stimulates neurogenesis in murine hippocampus in vivo.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

NSI-189 is an orally active benzylpiperizine-aminiopyridine compound with neurogenic activity, stimulates neurogenesis of human hippocampus-derived neural stem cells in vitro and stimulates neurogenesis in murine hippocampus in vivo.

Physicochemical Properties

M.Wt 366.51
Formula C22H30N4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(4-Benzylpiperazin-1-yl)(2-(isopentylamino)pyridin-3-yl)methanone

References

1. Fava M, et al. Mol Psychiatry. 2016 Oct;21(10):1372-80.

2. Tajiri N, et al. J Cell Physiol. 2017 Oct;232(10):2731-2740.

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