NSUN2 inhibitor AK (AK-968/36977265)

Chemical Structure : NSUN2 inhibitor AK

Catalog No.: PC-26591Not For Human Use, Lab Use Only.

NSUN2 inhibitor AK (AK-968/36977265) is a small molecule inhibitor of RNA methyltransferase NSUN2, decreases m5C occupancy and GATM mRNA levels, shows anti-fibrotic efficacy.

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Biological Activity

NSUN2 inhibitor AK (AK-968/36977265) is a small molecule inhibitor of RNA methyltransferase NSUN2, decreases m5C occupancy and GATM mRNA levels, shows anti-fibrotic efficacy.

Physicochemical Properties

M.Wt	339.36
Formula	C17H17N5O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-amino-3-(1-cyano-2-(3,4-dimethoxyphenyl)vinyl)-1-(2-hydroxyethyl)-1H-pyrazole-4-carbonitrile

References

1. Suo X, et al. Cell Rep. 2026 Apr 16;45(4):117253.

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