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NU-8165

Chemical Structure : NU-8165

CAS No.: 849723-20-2

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NU-8165 (NU8165;NU 8165)

Catalog No.: PC-60438Not For Human Use, Lab Use Only.

NU-8165 is a small molecule inhibitor of MDM2-p53 protein-protein interaction with IC50 of 16 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    NU-8165 is a small molecule inhibitor of MDM2-p53 protein-protein interaction with IC50 of 16 uM.

    Physicochemical Properties

    M.Wt 407.894
    Formula C24H22ClNO3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-benzyl-3-(4-chlorophenyl)-3-(3-hydroxypropoxy)isoindolin-1-one

    References

    1. Hardcastle IR, et al. J Med Chem. 2011 Mar 10;54(5):1233-43.

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