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NV01

Chemical Structure : NV01

CAS No.: 902908-03-6

NV01 (UHRF1 inhibitor NV01)

Catalog No.: PC-35121Not For Human Use, Lab Use Only.

NV01 is a small-molecule antagonist of the H3K9me3 binding to UHRF1 tandem tudor domain (TTD) with Kd of 5 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    NV01 is a small-molecule antagonist of the H3K9me3 binding to UHRF1 tandem tudor domain (TTD) with Kd of 5 uM.

    Physicochemical Properties

    M.Wt 375.491
    Formula C18H25N5O2S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(3-(diethylamino)propyl)-2-(5-methyl-8-oxothieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazin-7(8H)-yl)acetamide

    References

    1. Senisterra G, et al. SLAS Discov. 2018 Mar 1:2472555218766278.

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