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NVP-BDZ 824

Chemical Structure : NVP-BDZ 824

CAS No.: 916306-04-2

NVP-BDZ 824 (NVP-BDZ824;BDZ 824)

Catalog No.: PC-61173Not For Human Use, Lab Use Only.

NVP-BDZ 824 is a potent, highly selective antagonist of chemokine receptor CXCR3 with binding IC50 of 146 nM, Ca2+-mobilization IC50 of 28 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    NVP-BDZ 824 is a potent, highly selective antagonist of chemokine receptor CXCR3 with binding IC50 of 146 nM, Ca2+-mobilization IC50 of 28 nM.

    Physicochemical Properties

    M.Wt 442.563
    Formula C27H30N4O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (6aR,9R)-N9,N9-diethyl-N7-(o-tolyl)-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide

    References

    1. Thoma G, et al. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6185-8.

    2. Bernat V, et al. ChemMedChem. 2012 Aug;7(8):1481-9.

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