Chemical Structure : NVP-BSK805
CAS No.:
1092499-93-8
NVP-BSK805
(BSK 805;BSK-805;BSK805;NVP-BSK 805)
Catalog No. : PC-44039Not For Human Use, Lab Use Only.
NVP-BSK805 is a potent, selective and ATP-competitive inhibitor of JAK2 (V617F) and wt JAK2 (IC50=0.5 nM).
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4403901
Biological Activity
NVP-BSK805 is a potent, selective and ATP-competitive inhibitor of JAK2 (V617F) and wt JAK2 (IC50=0.5 nM).
Physicochemical Properties
M.Wt
490.5476
Formula
C27H28F2N6O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Quinoxaline, 8-[3,5-difluoro-4-(4-morpholinylmethyl)phenyl]-2-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-
References
1. Baffert F, et al. Mol Cancer Ther.
2. Pissot-Soldermann C, et al. Bioorg Med Chem Lett.
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