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Nek2 inhibitor 11

Chemical Structure : Nek2 inhibitor 11

CAS No.:

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Nek2 inhibitor 11

Catalog No.: PC-61477Not For Human Use, Lab Use Only.

Nek2 inhibitor 11 is a potent, ATP-competitive and relative selective Nek2 inhibitor with IC50 of 0.67 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Nek2 inhibitor 11 is a potent, ATP-competitive and relative selective Nek2 inhibitor with IC50 of 0.67 uM.
    Nek2 inhibitor 11 displays >10-fold selectivity over CDK2.

    Physicochemical Properties

    M.Wt 394.479
    Formula C21H26N6O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    3-((6-(cyclohexylmethoxy)-9H-purin-2-yl)amino)-N,N-dimethylbenzamide

    References

    1. Coxon CR, et al. Oncotarget. 2017 Mar 21;8(12):19089-19124.

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