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Neladenoson dalanate hydrochloride

Chemical Structure : Neladenoson dalanate hydrochloride

CAS No.: 1239235-25-6

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Neladenoson dalanate hydrochloride (BAY 10-67197)

Catalog No.: PC-63435Not For Human Use, Lab Use Only.

Neladenoson dalanate (BAY 10-67197) is a potent, selective, orally acitve partial adenosine A1 receptor (A1AR) agonist (EC50=0.1 nM) for the treatment of chronic heart failure.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Neladenoson dalanate (BAY 10-67197) is a potent, selective, orally acitve partial adenosine A1 receptor (A1AR) agonist (EC50=0.1 nM) for the treatment of chronic heart failure.

    Physicochemical Properties

    M.Wt 752.73
    Formula C35H35Cl2N7O4S2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-{4-[2-({[2-(4-chlorophenyl)-1,3-thiazol- 4-yl]methyl}sulfanyl)-3,5-dicyano-6-(pyrrolidin-1-yl)pyridin- 4-yl]phenoxy}ethyl L-alanyl-L-alaninate hydrochloride

    References

    1. Meibom D, et al. ChemMedChem. 2017 May 22;12(10):728-737.

    2. Voors AA, et al. J Clin Pharmacol. 2017 Apr;57(4):440-451.

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