Chemical Structure : Nitisinone
CAS No.: 104206-65-7
Catalog No.: PC-21242Not For Human Use, Lab Use Only.
Nitisinone (NTBC, Nitisone, SC0735) is a potent, orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with IC50 of 173 nM.
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Nitisinone (NTBC, Nitisone, SC0735) is a potent, orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with IC50 of 173 nM.
Nitisinone (NTBC, Nitisone, SC0735) promotes tyrosine accumulation in a dose-dependent manner.
4-HPPD is a target for treating type I tyrosinemia and other diseases with defects in tyrosine catabolism.
M.Wt | 329.23 | |
Formula | C14H10F3NO5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-(2-nitro-4-(trifluoromethyl)benzoyl)cyclohexane-1,3-dione |
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