Chemical Structure : Nodinitib-1
CAS No.: 799264-47-4
Catalog No.: PC-45499Not For Human Use, Lab Use Only.
Nodinitib-1 (ML130, Noditinib 1) is a potent and selective NOD1 inhibitor with IC50 of 0.56 uM.
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|---|---|---|---|
| 10 mg | $58 | In stock | |
| 25 mg | $98 | In stock | |
| 50 mg | $158 | In stock | |
| 100 mg | Get quote |
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Nodinitib-1 (ML130, Noditinib 1) is a potent and selective NOD1 inhibitor with IC50 of 0.56 uM.
Nodinitib-1 (ML130) shows no inhibition on NOD1, TNFα (IC50> 20 uM) and dIKKγ/NEMO, MYD88, FLIP, CARD6, APAF1 or NLRC4.
Nodinitib-1 (ML130) inhibits IL-8 production induced by NOD1 ligand and γ-tri-DAP-induced expression of the prototypical NF-κB target gene IκBα at the mRNA level.
| M.Wt | 287.3369 | |
| Formula | C14H13N3O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: 20 mg/mL |
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| Chemical Name/SMILES |
1H-Benzimidazol-2-amine, 1-[(4-methylphenyl)sulfonyl]- |
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1. Correa RG, et al. Chem Biol. 2011 Jul 29;18(7):825-32.
2. Khan PM, et al. ACS Med Chem Lett. 2011 Oct 13;2(10):780-785.
3. Zheng W, et al. Biochem Biophys Res Commun. 2012 Apr 20;420(4):762-7.

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