Nolatrexed | Antifolate | Probechem Biochemicals

Chemical Structure : Nolatrexed

CAS No.: 152946-68-4

Catalog No.: PC-26408Not For Human Use, Lab Use Only.

Nolatrexed (AG337) is an orally active antifolate agent and thymidylate synthase (TS) inhibitor.

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25 mg	$128	In stock
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Biological Activity

Nolatrexed (AG337) is an orally active antifolate agent and thymidylate synthase (TS) inhibitor.

M.Wt	357.25
Formula	C14H14Cl2N4OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Amino-6-methyl-5-(pyridin-4-ylthio)quinazolin-4(1H)-one dihydrochloride

1. Dash AK, et al. J Pharm Sci. 1996 Oct;85(10):1123-7.

2. Rafi I, et al. Clin Cancer Res. 1995 Nov;1(11):1275-84.