Nurr1 agonist 28

Chemical Structure : Nurr1 agonist 28

Catalog No.: PC-27064Not For Human Use, Lab Use Only.

Nurr1 agonist 28 is a potent, selective and brain-penetrant Nurr1 (NR4A2) agonist with EC50 of 7 nM, shows effects of Nurr1 activation in the central nervous system (CNS).

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Biological Activity

Nurr1 agonist 28 is a potent, selective and brain-penetrant Nurr1 (NR4A2) agonist with EC50 of 7 nM, shows effects of Nurr1 activation in the central nervous system (CNS).

Physicochemical Properties

M.Wt	427.39
Formula	C19H9D3F4N2O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2,3,5,6-tetrafluoro-3'-(methoxy-d3)-[1,1'-biphenyl]-4-yl)thiophene-3,4-dicarboxamide

References

1. Vietor J, et al. ChemMedChem. 2026 Jun 15;21(11):e70296.

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Nurr1 agonist 28

Biological Activity

Physicochemical Properties

References

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