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Chemical Structure : Nutlin-3b
CAS No.: 675576-97-3
Catalog No.: PC-44349Not For Human Use, Lab Use Only.
A p53/MDM2 antagonist or inhibitor with IC50 value of 13.6 μM, 150-fold less potent (+)-enantiomer of Nutlin-3 as in comparison with opposite (-)-enantiomer Nutlin-3a. .
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $160 | In stock | |
| 50 mg | $600 | In stock |
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A p53/MDM2 antagonist or inhibitor with IC50 value of 13.6 μM, 150-fold less potent (+)-enantiomer of Nutlin-3 as in comparison with opposite (-)-enantiomer Nutlin-3a.
| M.Wt | 581.4896 | |
| Formula | C30H30Cl2N4O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-Piperazinone, 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]- |
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1. Vassilev LT, et al. Science, 2004, 303(5659), 844-848.
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