Nuvrumetinib (PAS-004) | MEK1/2 inhibitor

Chemical Structure : Nuvrumetinib

Catalog No.: PC-27483Not For Human Use, Lab Use Only.

Nuvrumetinib (PAS-004) is a potent, selective, next-generation macrocyclic MEK1/2 inhibitor.

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Biological Activity

Nuvrumetinib (PAS-004) is a potent, selective, next-generation macrocyclic MEK1/2 inhibitor.

M.Wt	570.32
Formula	C19H18F3IN2O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Spiro[1H,3H-8,2,1-benzoxathiazecine-3,1′-cyclopropane]-5,6-diol, 10,11-difluoro-12-[(2-fluoro-4-iodophenyl)amino]-4,5,6,7-tetrahydro-, 2,2-dioxide, (5R,6S)-

1. Patent WO2025147503 A1 2025-07-10.