Catalog No.: PC-43251Not For Human Use, Lab Use Only.
OBA-09 is a simple ester of pyruvate and salicylic acid, main metabolites of pyruvate and aspirin, respectively, exerts robust neuroprotective effect in the postischemic brain in vivo.
OBA-09 is a simple ester of pyruvate and salicylic acid, main metabolites of pyruvate and aspirin, respectively, exerts robust neuroprotective effect in the postischemic brain in vivo.
OBA-09 is designed to incorporate pyruvate and salicylic acid and to release them slowly in vivo via ester hydrolysis.
OBA-09 exhibits antioxidative effects in the postischemic brain, also exerts anti-excitotoxic and anti-Zn(2+)-toxic functions.
OBA-09 has a potent therapeutic potential as a multimodal neuroprotectant in the postischemic brain.
Physicochemical Properties
M.Wt
208.1675
Formula
C10H8O5
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Benzoic acid, 2-(1,2-dioxopropoxy)-
References
1. Kim SW, et al. Mol Pharmacol. 2011 Feb;79(2):220-8.
2. Lee HK, et al. Brain Res. 2013 Aug 28;1528:68-79.
