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OBA-09

Chemical Structure : OBA-09

CAS No.: 856095-68-6

OBA-09 (OBA09)

Catalog No.: PC-43251Not For Human Use, Lab Use Only.

OBA-09 is a simple ester of pyruvate and salicylic acid, main metabolites of pyruvate and aspirin, respectively, exerts robust neuroprotective effect in the postischemic brain in vivo.

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Biological Activity

OBA-09 is a simple ester of pyruvate and salicylic acid, main metabolites of pyruvate and aspirin, respectively, exerts robust neuroprotective effect in the postischemic brain in vivo.
OBA-09 is designed to incorporate pyruvate and salicylic acid and to release them slowly in vivo via ester hydrolysis.
OBA-09 exhibits antioxidative effects in the postischemic brain, also exerts anti-excitotoxic and anti-Zn(2+)-toxic functions.
OBA-09 has a potent therapeutic potential as a multimodal neuroprotectant in the postischemic brain.

Physicochemical Properties

M.Wt 208.1675
Formula C10H8O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzoic acid, 2-(1,2-dioxopropoxy)-

References

1. Kim SW, et al. Mol Pharmacol. 2011 Feb;79(2):220-8.

2. Lee HK, et al. Brain Res. 2013 Aug 28;1528:68-79.

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