Chemical Structure : OBA-09
Catalog No.: PC-43251Not For Human Use, Lab Use Only.
OBA-09 is a simple ester of pyruvate and salicylic acid, main metabolites of pyruvate and aspirin, respectively, exerts robust neuroprotective effect in the postischemic brain in vivo.
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OBA-09 is a simple ester of pyruvate and salicylic acid, main metabolites of pyruvate and aspirin, respectively, exerts robust neuroprotective effect in the postischemic brain in vivo; OBA-09 is designed to incorporate pyruvate and salicylic acid and to release them slowly in vivo via ester hydrolysis; exhibits antioxidative effects in the postischemic brain, also exerts anti-excitotoxic and anti-Zn(2+)-toxic functions; OBA-09 has a potent therapeutic potential as a multimodal neuroprotectant in the postischemic brain.
M.Wt | 208.1675 | |
Formula | C10H8O5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Kim SW, et al. Mol Pharmacol. 2011 Feb;79(2):220-8.
2. Lee HK, et al. Brain Res. 2013 Aug 28;1528:68-79.
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