Chemical Structure : OG-L002
CAS No.: 1357302-64-7
Catalog No.: PC-61746Not For Human Use, Lab Use Only.
OG-L002 is a novel selective LSD1 inhibitor with IC50 of 20 nM.
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OG-L002 is a potent, selective LSD1 inhibitor with IC50 of 20 nM.
OG-L002 demonstrates significant potency both in inhibition of HSV IE gene expression and in suppression of viral reactivation from latency in a mouse ganglion explant model.
OG-L002 also suppresses the expression of the initial class of hCMV and adenovirus genes in vitro.
OG-L002 reduces the induction of TNF-α mRNA in splenocytes from mice.
M.Wt | 225.3 | |
Formula | C15H15NO | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4'-[(1R,2S)-2-aminocyclopropyl]-[1,1'-biphenyl]-3-ol |
1. Seifermann M, et al. DNA Repair (Amst). 2017 Oct;58:13-20.
2. Liang Y, et al. MBio. 2013 Feb 5;4(1):e00558-12.
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