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OG-L002

Chemical Structure : OG-L002

CAS No.: 1357302-64-7

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OG-L002 (OG L002)

Catalog No.: PC-61746Not For Human Use, Lab Use Only.

OG-L002 is a novel selective LSD1 inhibitor with IC50 of 20 nM.

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10 mg $118 In stock
25 mg $188 In stock
50 mg $298 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

OG-L002 is a potent, selective LSD1 inhibitor with IC50 of 20 nM.
OG-L002 demonstrates significant potency both in inhibition of HSV IE gene expression and in suppression of viral reactivation from latency in a mouse ganglion explant model.
OG-L002 also suppresses the expression of the initial class of hCMV and adenovirus genes in vitro.
OG-L002 reduces the induction of TNF-α mRNA in splenocytes from mice.

Physicochemical Properties

M.Wt 225.3
Formula C15H15NO
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4'-[(1R,2S)-2-aminocyclopropyl]-[1,1'-biphenyl]-3-ol

References

1. Seifermann M, et al. DNA Repair (Amst). 2017 Oct;58:13-20.

2. Liang Y, et al. MBio. 2013 Feb 5;4(1):e00558-12.

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