OGG1 inhibitor O8 | OGG1 inhibitor | Probechem Biochemicals

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Chemical Structure : OGG1 inhibitor O8

CAS No.: 350997-39-6

OGG1 inhibitor O8 (OGG1 inhibitor 08)

Catalog No.: PC-35807Not For Human Use, Lab Use Only.

OGG1 inhibitor O8 is a potent, selective inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1) with IC50 of 0.22 uM, displays no significant activity against other DNA Glycosylases (NEIL1, NTH1, Fpg, IC50>50 uM).

Packing	Price	Stock
10 mg	$88	In stock
25 mg	$138	In stock
50 mg	$218	In stock
100 mg	$368	In stock
250 mg		Get quote

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

OGG1 inhibitor O8 is a potent, selective inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1) with IC50 of 0.22 uM, displays no significant activity against other DNA Glycosylases (NEIL1, NTH1, Fpg, IC50>50 uM).

Physicochemical Properties

M.Wt	261.12
Formula	C9H6Cl2N2OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3,4-dichlorobenzo[b]thiophene-2-carbohydrazide

References

1. Donley N, et al. ACS Chem Biol. 2015 Oct 16;10(10):2334-43. doi: 10.1021/acschembio.5b00452.

2. Visnes T, et al. Science. 2018 Nov 16;362(6416):834-839.

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OGG1 inhibitor O8 (OGG1 inhibitor 08)

Biological Activity

Physicochemical Properties

References

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