Chemical Structure : OSS-128167
CAS No.: 887686-02-4
Catalog No.: PC-63273Not For Human Use, Lab Use Only.
OSS-128167 is a novel selective, cell permeable SIRT6 inhibitor with IC50 of 89, 1578 and 751 uM for SIRT6, SIRT1 and SIRT2, respectively.
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OSS-128167 is a novel selective, cell permeable SIRT6 inhibitor with IC50 of 89, 1578 and 751 uM for SIRT6, SIRT1 and SIRT2, respectively.
OSS-128167 increases H3K9 acetylation and GLUT-1 expression in treated cells.
M.Wt | 366.329 | |
Formula | C19H14N2O6 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
5-[[3-[(2-Furanylcarbonyl)amino]benzoyl]amino]-2-hydroxybenzoic acid |
1. Parenti MD, et al. J Med Chem. 2014 Jun 12;57(11):4796-804.
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