OSS-128167 (OSS_128167) | SIRT6 inhibitor

Chemical Structure : OSS-128167

CAS No.: 887686-02-4

OSS-128167 (OSS128167, OSS_128167)

Catalog No.: PC-63273Not For Human Use, Lab Use Only.

OSS-128167 (OSS_128167) is a novel selective, cell permeable SIRT6 inhibitor with IC50 of 89, 1578 and 751 uM for SIRT6, SIRT1 and SIRT2, respectively.

Packing	Price	Stock
5 mg	$88	In stock
10 mg	$128	In stock
25 mg	$218	In stock
50 mg	$358	In stock
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Biological Activity

OSS-128167 (OSS_128167) is a novel selective, cell permeable SIRT6 inhibitor with IC50 of 89, 1578 and 751 uM for SIRT6, SIRT1 and SIRT2, respectively.
OSS-128167 increases H3K9 acetylation and GLUT-1 expression in treated cells.

Physicochemical Properties

M.Wt	366.329
Formula	C19H14N2O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-[[3-[(2-Furanylcarbonyl)amino]benzoyl]amino]-2-hydroxybenzoic acid

References

1. Parenti MD, et al. J Med Chem. 2014 Jun 12;57(11):4796-804.

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OSS-128167 (OSS128167, OSS_128167)

Biological Activity

Physicochemical Properties

References

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