OSSK-674842 | CFTR potentiator | ProbeChem Biochemicals

Chemical Structure : OSSK-674842

OSSK-674842 (OSSK-2, OSSK 674842)

Catalog No.: PC-70167Not For Human Use, Lab Use Only.

A novel potent CFTR potentiator that blocks hCFTR with apparent Kd of 71.3 uM.

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Biological Activity

OSSK-674842 is a novel potent CFTR potentiator that blocks hCFTR with apparent Kd of 71.3 uM.
OSSK-674842 potentially serves as lead compound for development of new drugs for the treatment of cystic fibrosis.

Physicochemical Properties

M.Wt	457.122
Formula	C16H15Br2N3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-N'-(3,5-dibromo-2,4-dihydroxybenzylidene)-2-(p-tolylamino)acetohydrazide

References

1. Cui G, et al. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L192-207.

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OSSK-674842 (OSSK-2, OSSK 674842)

Biological Activity

Physicochemical Properties

References

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