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OSSK-674842

Chemical Structure : OSSK-674842

CAS No.: 2054944-80-6

OSSK-674842 (OSSK-2, OSSK 674842)

Catalog No.: PC-70167Not For Human Use, Lab Use Only.

A novel potent CFTR potentiator that blocks hCFTR with apparent Kd of 71.3 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    OSSK-674842 is a novel potent CFTR potentiator that blocks hCFTR with apparent Kd of 71.3 uM.
    OSSK-674842 potentially serves as lead compound for development of new drugs for the treatment of cystic fibrosis.

    Physicochemical Properties

    M.Wt 457.122
    Formula C16H15Br2N3O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (E)-N'-(3,5-dibromo-2,4-dihydroxybenzylidene)-2-(p-tolylamino)acetohydrazide

    References

    1. Cui G, et al. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L192-207.

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