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Chemical Structure : OSU-6162 hydrochloride
Catalog No.: PC-70063Not For Human Use, Lab Use Only.
A potent dopamine stabilizer with Ki of 447 and 1305 nM for D2 and D3 receptors respectively.
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A potent dopamine stabilizer with Ki of 447 and 1305 nM for D2 and D3 receptors respectively; lacks high affinity for various neuroreceptors in vitro (Ki>1 uM); has antipsychotic, anti-addictive and anti-Parkinsonian effects in animal studies; the (R) enantiomer (+)-OSU-6162 has higher efficacy at 5-HT2A but lower D2 affinity.
| M.Wt | 589.17 | |
| Formula | C33H41ClN6O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ekesbo A, et al. Neuroreport. 1997 Jul 28;8(11):2567-70.
2. Nichols NF, et al. Neuropharmacology. 2002 Oct;43(5):817-24.
3. Kara E, et al. Br J Pharmacol. 2010 Nov;161(6):1343-50.
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