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Chemical Structure : Olinone
Catalog No.: PC-62475Not For Human Use, Lab Use Only.
Olinone is a selective inhibitor for the BET BRD1 with Kd of 3.4/3.7/8.6 uM for BRD4-BrD1/BRD3-BrD1/BRD2-BrD1, respectively, shows high selectivity over BET BRD2 (Kd>300 uM).
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Olinone is a selective inhibitor for the BET BRD1 with Kd of 3.4/3.7/8.6 uM for BRD4-BrD1/BRD3-BrD1/BRD2-BrD1, respectively, shows high selectivity over BET BRD2 (Kd>300 uM).
Olinone accelerates the progression of mouse primary oligodendrocyte progenitors toward differentiation.
| M.Wt | 299.374 | |
| Formula | C17H21N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Gacias M, et al. Chem Biol. 2014 Jul 17;21(7):841-54.
2. Chiang CM. Chem Biol. 2014 Jul 17;21(7):804-6.
3. Zhao L, et al. J Neuroinflammation. 2017 Jan 19;14(1):14.al.
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