Chemical Structure : Olomoucine
CAS No.:
101622-51-9
Olomoucine
(CDK inhibitor)
Catalog No. : PC-60188Not For Human Use, Lab Use Only.
Olomoucine is a potent, ATP-competetive CDKs inhibitor with IC50 of 7, 7, 7, 3 uM for Cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk/p35 kinase.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6018801
Biological Activity
Olomoucine is a potent, ATP-competetive CDKs inhibitor with IC50 of 7, 7, 7, 3 uM for Cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk/p35 kinase.
Physicochemical Properties
M.Wt
298.35
Formula
C15H18N6O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-(2-Hydroxyethylamino)-6- benzylamino-9-methylpurine
References
1. Veselý J, et al. Eur J Biochem
2. Tsou YC, et al. Neurosci Lett.
3. Fei XF, et al. Brain Res
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