Catalog No.: PC-43087Not For Human Use, Lab Use Only.
Oltipraz (RP 35972, NSC 347901) is a cancer chemopreventive agent with inhibitory effect on angiogenesis and tumor growth, inhibits insulin- or hypoxia-induced HIF-1α expression through an increase in ubiquitination.
Oltipraz (RP 35972, NSC 347901) is a cancer chemopreventive agent with inhibitory effect on angiogenesis and tumor growth, inhibits insulin- or hypoxia-induced HIF-1α expression through an increase in ubiquitination.
Oltipraz (RP 35972, NSC 347901) abrogates insulin-induced H(2)O(2) production, thereby preventing H(2)O(2)-enhanced HIF-1alpha expression and promoting its ubiquitination and degradation.
Oltipraz (RP 35972, NSC 347901) inhibits HIF-1α activity and HIF-1α-dependent tumor growth both in vitro and in vivo.
