Chemical Structure : Omuralide
CAS No.: 154226-60-5
Catalog No.: PC-61314Not For Human Use, Lab Use Only.
Omuralide (Clasto-lactacystin) is a potent 20S proteasome inhibitor with IC50 of 49 nM (inhibition of proteasomal chymotrypsin-like proteolytic activity).
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Omuralide (Clasto-lactacystin) is a potent 20S proteasome inhibitor with IC50 of 49 nM (inhibition of proteasomal chymotrypsin-like proteolytic activity).
M.Wt | 213.233 | |
Formula | C10H15NO4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(1R,4R,5S)-1-[(1S)-1-Hydroxy-2-methylpropyl]-4-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione |
1. Corey EJ, et al. Chem Pharm Bull (Tokyo). 1999 Jan;47(1):1-10.
2. List A, et al. Angew Chem Int Ed Engl. 2014 Jan 7;53(2):571-4.
3. Feling RH, et al. Angew Chem Int Ed Engl. 2003 Jan 20;42(3):355-7.
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