Omuralide | 20S proteasome inhibitor | Probechem Biochemicals

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Chemical Structure : Omuralide

CAS No.: 154226-60-5

Omuralide (Clasto-lactacystin, β-Clastolactacystin)

Catalog No.: PC-61314Not For Human Use, Lab Use Only.

Omuralide (Clasto-lactacystin) is a potent 20S proteasome inhibitor with IC50 of 49 nM (inhibition of proteasomal chymotrypsin-like proteolytic activity).

Packing	Price	Stock
50 ug	$158	In stock
100 ug	$258	In stock
500 ug	$858	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Omuralide (Clasto-lactacystin) is a potent 20S proteasome inhibitor with IC50 of 49 nM (inhibition of proteasomal chymotrypsin-like proteolytic activity).

Physicochemical Properties

M.Wt	213.233
Formula	C10H15NO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(1R,4R,5S)-1-[(1S)-1-Hydroxy-2-methylpropyl]-4-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione

References

1. Corey EJ, et al. Chem Pharm Bull (Tokyo). 1999 Jan;47(1):1-10.

2. List A, et al. Angew Chem Int Ed Engl. 2014 Jan 7;53(2):571-4.

3. Feling RH, et al. Angew Chem Int Ed Engl. 2003 Jan 20;42(3):355-7.

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Omuralide (Clasto-lactacystin, β-Clastolactacystin)

Biological Activity

Physicochemical Properties

References

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